Newcomer Supply Spirochete Treponema sp., Artificial Control Slides are for the positive immunohistochemical staining of spirochetes, the causative agent of a variety of diseases such as; syphilis, bejel, pinta, yaws and lyme. Treponema hyodysenteriae purchased from American Type Culture Collection is used to produce the positive control tissue. Spirochete Treponema sp., Artificial Control Slides contain sections of positive staining rat lung and negative staining human lung.